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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Mapping actionable pathways and mutations in brain tumours using targeted RNA next generation sequencing

Fig. 6

Actionable markers in brain tumours. a overview of expression of potentially actionable targets in a subset of patients, expressed as fold change compared to the mean of the entire group. For clarity only tyrosine kinases are shown for a small selection of patients. b comparative analysis of a primary pleomorphous xantoastrocytoma and its recurrence 4 years later. c shows a selection of actionable targets in sample 13–05, a metastasis of a lung cancer. Note high expression levels of the macrophage receptor RON, MET and CTLA-4. Also VEGF isoforms 121 and 189 are detected

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Acta Neuropathologica Communications

ISSN: 2051-5960

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