Fig. 5From: Phosphorylated TDP-43 aggregates in skeletal and cardiac muscle are a marker of myogenic degeneration in amyotrophic lateral sclerosis and various conditionsContiguous sections of the tongue immunostained with anti-pTDP-43 without proteinase K treatment (a and c) and with proteinase K treatment (b and d) in a patient with ALS (case B-22). Proteinase K treatment for 10 min decreases the number of short linear inclusions (a and b), whereas dense filamentous inclusions are proteinase K-resistant (c and d). Bars = 20 μmBack to article page