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Fig. 8 | Acta Neuropathologica Communications

Fig. 8

From: A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain

Fig. 8

iPSC-derived neurons do not recapitulate the tau PTM signature. a) Analysis of multimers by Tau12-Tau12 electrochemiluminescence assay with and without boiling of lysates from controls, familial AD (fAD) and sporadic AD (sAD) neurons with SDS. b) Normalized PTM signals (pS198, pS199, pT231 and pS416). None of the observed changes were significant (p > 0.05, t-tests)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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