Fig. 13
From: DNA repair deficiency and senescence in concussed professional athletes involved in contact sports
Correlation between proteinopathy and stage of yH2AX distribution in cases and controls with no mTBI history. The presence of a proteinopathy was significantly correlated with higher levels of DNA damage in brains with a history of mTBI (p = 0.04, Mann-Whitney Rank Sum Test). Cases with a proteinopathy presented with abnormal accumulation of at least one of the following proteins: p-tau, β-amyloid, α-synuclein, or TDP-43. Individuals with no proteinopathy did not present with abnormal accumulation of any of the listed proteins