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Table 2 Multivariate Cox-regression analysis. Mitotic activity was analyzed as continuous parameter

From: Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features – a retrospective analysis of the HIT ependymoma trial cohort

Event-free Survival
CovariateCoefficientStdErrWald Chi-SquareP Value
1q Gain0.6840.2726,2950.012
Resection1.0530.25517,072<0.001
Mitotic activity (cont.)0.0080.0035.8260.016
CovariateHazard Ratio95%Conf-L95%Conf-U 
1q Gain1.9641.1613.389 
Resection2.8661.7394.723 
Mitotic activity (cont.)1.0081.0021.015 
Overall Survival
CovariateCoefficientStdErrWald Chi-SquareP Value
1q Gain0.8970.3745.7540.016
Resection1.1240.3818.7030.003
Mitotic activity (cont.)0.0150.00510.5740.001
Necrosis0.7390.7630.9370.333
Vascular proliferation1.4310.7523.6190.057
CovariateHazard Ratio95%Conf-L95%Conf-U 
1q Gain2.4531.1785.107 
Resection3.0781.4586.496 
Mitotic activity (cont.)1.0151.0061.024 
Necrosis2.0940.4699.351 
Vascular proliferation4.1810.95818.253