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Table 5 Table summarizing the outcome of the linear mixed model statistical analyses of the different regions of the DMN (after FDR correction for multiple comparison of p < 0.05). Abbreviations: see Table 2

From: Increased soluble amyloid-beta causes early aberrant brain network hypersynchronisation in a mature-onset mouse model of amyloidosis

Connection (within DMN)Effectp-value
Cg1-Cg2+RSplb[Genotype*Time]W28, TG < Ctrl (p = 0.0001)
Cg1-Fr[Genotype*Time]W8, TG > Ctrl (p = 0.0473)
W28, TG < Ctrl (p = 0.0221)
Cg1-PtA[Genotype*Time]W8, TG > Ctrl (p = 0.0393)
W28, TG < Ctrl (p = 0.0005)
Cg1-RSpl[Genotype*Time]W8, TG > Ctrl (p = 0.0482)
W28, TG < Ctrl (p = 0.0096)
Cg2+RSplb-Fr[Genotype*Time]Trend W8 TG > Ctrl (p = 0.0745)
Trend W16 TG < Ctrl (p = 0.0638)
Cg2+RSplb-PtA[Genotype*Time]W28, TG < Ctrl (p = 0.0002)
RSpl-PtA[Genotype*Time]Trend W8 TG > Ctrl (p = 0.0514)
W28 TG < Ctrl (p = 0.0224)
HC-Cg1Timep = 0.0212
HC-Cg2+RSplbTimep = 0.0212
HC-FrGenotypep = 0.0349
PtA-FrGenotypep = 0.025
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Acta Neuropathologica Communications

ISSN: 2051-5960

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