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Table 4 Table summarizing the outcome of the linear mixed model statistical analyses of the different regions of the DMN. Abbreviations: see Table 2

From: Increased soluble amyloid-beta causes early aberrant brain network hypersynchronisation in a mature-onset mouse model of amyloidosis

Region (within DMN)

Effect

p-value

HC

Time

p = 0.0006

[Genotype*Time]

W8, TG > Ctrl (p = 0.0087)

trend W28 TG < Ctrl (p = 0.079)

Cg1

Time

p = 0.0479

[Genotype*Time]

W8, TG > Ctrl (p = 0.0443)

W28, TG < Ctrl (p < 0.0001)

Cg2+RSplb

Time

p = 0.0202

[Genotype*Time]

Trend W8, TG > Ctrl (p = 0.07)

W28, TG < Ctrl (p = 0.0003)

RSpl

[Genotype*Time]

W8, TG > Ctrl (p = 0.0233)

W28, TG < Ctrl (p = 0.0132)

PtA

[Genotype*Time]

W8, TG > Ctrl (p = 0.007)

W28, TG < Ctrl (p = 0.0031)

Fr

Time

p = 0.026

[Genotype*Time]

trend W0, TG > Ctrl (p = 0.0723)

W8, TG > Ctrl (p=0.0027)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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