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Table 1 Differentially secreted proteins from control and Smn KD H-2Kb-BL6 muscle cells (p < 0.05)

From: Muscle regulates mTOR dependent axonal local translation in motor neurons via CTRP3 secretion: implications for a neuromuscular disorder, spinal muscular atrophy

Gene name Protein name # of unique peptides P value Fold change
SmnKD/Cont
GO/KEGG
Vapa Vesicle-associated membrane protein-associated protein A 2 0.0028 4.903 Tight junction
Cxcl1 Fractalkine 3 0.0220 1.365 Chemokine signaling
exosome
Dpp2 Dipeptidyl peptidase 2 5 0.0063 1.286 exosome
Serpinh1 Serpin H1 15 0.0331 1.182  
Timp1 Metalloproteinase inhibitor 1 6 0.0293 1.167 Exosome
Alad Delta-aminolevulinic acid dehydratase 7 0.0132 1.165  
Col4a1 Arresten;Collagen alpha-1(IV) chain 33 0.0209 1.140 Extracellular matrix, exosome
Lgals1 Galectin-1 8 0.0142 1.139 exosome
Serpine2 Glia-derived nexin 9 0.0386 1.109 exosome
Rcn1 Reticulocalbin-1 6 0.0138 1.101 Ca2+ binding
Msn Moesin 23 0.0140 1.071 Actin cytoskeleton, cell junction, exosome
Lgal3bp Galectin-3-binding protein 5 0.0353 1.070 exosome
Lsyna1 Inositol-3-phosphate synthase 1 7 0.0411 0.920  
Atp5j2 ATP synthase subunit f, mitochondrial 1 0.0414 0.914 ATP synthesis, oxidative `phosphorylation
Tbl1xr1 F-box-like/WD repeat-containing protein TBL1XR1 2 0.0346 0.907 Wnt pathway,
Actn2 Alpha-actinin-2 22 0.0364 0.885 Cell junction, actin cytoskeleton
Xirp1 Xin actin-binding repeat-containing protein 1 4 0.0295 0.871 Cell junction, actin cytoskeleton
Uqcrc1 Cytochrome b-c1 complex subunit 1, mitochondrial 7 0.0206 0.852 Oxidative phosphorylation, Alzheimer’s, Parkinson’s, Huntington diseases
Phb2 Prohibitin-2 7 0.0082 0.845  
Ermp1 Endoplasmic reticulum metallopeptidase 1 2 0.0099 0.841  
Col4a2 Canstatin; Collagen alpha-2(IV) chain 36 0.0454 0.655 Focal adhesion, exosome
Col5a2 Collagen alpha-2(V) chain 37 0.0008 0.592 Focal adhesion, exosome
C1qtnf3 Complement C1q tumor necrosis factor-related protein 3 3 7.77E-0.5 0.455 Glucose homeostasis, exosome
Cp Ceruloplasmin 2 0.0313 0.402 Cu-oxidase, exosome
Serpinc1 Antithrombin-III 5 0.0049 0.391 Complement and coagulation cascades, endopeptidase inhibitor, exosome