Fig. 6
From: Immune landscapes associated with different glioblastoma molecular subtypes
Macrophages and microglia are the predominant immune cells in GBM and their percentages differ across the molecular subtypes. a and b show classical, mesenchymal, neural and proneural GBMs stained for CD68 and CD163 (brown). In c, mesenchymal GBMs display the highest percentage of CD68 positive cells. In d, CD163 positive cells represent more than 80% of mesenchymal GBM cellularity, account this molecular subtype the most infiltrated by this cellular subtype. Significant difference in CD163 infiltrate was also observed between PN and CL GBMs. Scale bar 100 μm. Arrowheads indicate representative positive cells. CL, classical; MES, mesenchymal; N, neural; P, proneural. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001