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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Optimization of ultrastructural preservation of human brain for transmission electron microscopy after long post-mortem intervals

Fig. 1

Electron micrographs of human brain samples (case 5) with and without post fixation with osmium tetroxide before the HPF. On the left side, the layers of the myelin sheath remain compact compared to the sample without post-fixation on the right side. In the left image, some proteins with good accessibility showed strong staining. Both samples were prepared with the cryo-substitution cocktail I; Scale bars = 0.2 μm

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