Fig. 4

Deregulation of inflammatory pathways in NestinCre;STOPfloxc-MYC CPT. a Normalized c-MYC expression values (CPM) of 3 murine control and 3 CPT samples. Median and interquartile range are depicted. b IPA analysis on differentially expressed genes (n = 245) between murine CPT and control samples. Positive z-score is associated with enrichment in the CPT context. c Unsupervised hierarchical clustering analysis and relative expression of c-MYC-correlated genes in the murine context (n = 2290), across control and CPT samples. d Unsupervised hierarchical clustering analysis and relative expression of murine orthologs of c-MYC-correlated genes in the human context (n = 356), across control and CPT samples