Fig. 4
From: Cerebrospinal fluid from Alzheimer’s disease patients promotes tau aggregation in transgenic mice
Gallyas-Braak stainings. Overview on the hippocampus (CTR CSF: a, AD CSF: b). Increase in Gallyas-Braak positive hippocampal neurons in AD CSF seeded mice compared to CTR CSF seedings (c, p = 0.0007). Gallyas positive neurons in the CA1 subfield (CTR CSF: d, AD CSF: e). Focal dot-like Gallyas-Braak positive structures in the ipsilateral alveus above the CA1 field after inoculation of CSF from patient #2 (f, arrow), and in the ipsilateral dorsal fornix after seeding with CSF from patient #1 (g). Numbers indicate neurons per area. Scale bar in a equals 500 μm in a and b; scale bar in d equals 100 μm and applies to d-f; scale bar in g equals 76 μm