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Table 2 Immunohistochemical characteristics of pituicytomas

From: Histologic, immunohistochemical, and molecular features of pituicytomas and atypical pituicytomas

Patient TTF-1 EMA S100 GFAP Synapto-physin Ki-67 SSTR2A pERK BRAF V600E
1 + + Focal + + 3% + +
2 + + < 1% +
3 + + + NP 4% Focal +
4 + NP Focal + Focal + NP +
5 + NP NP + NP <  1% + NP
6 + + + + NP <  1% NP + NP
7 + Focal + + Focal + NP 1–3% + NP
8 + NP + NP NP NP +
9 + Focal + NP <  1% + NP
10 (1)a + NP NP 5% NP NP NP
10 (2)a + NP 10% NP NP NP
10 (3)a + NP NP NP NP NP NP
10 (4)a + NP NP 10% Focal + +
11a + + + 10% +
% Positive 100.0% 33.3% 88.9% 50.0% 33.3%   20.0% 90.9% 14.3%
  1. Patient 10 had four separate resections as indicated by the parentheses. Abbreviations: + positive; - negative, NP not performed
  2. aatypical pituicytoma