Table 2 Immunohistochemical characteristics of pituicytomas
From: Histologic, immunohistochemical, and molecular features of pituicytomas and atypical pituicytomas
Patient | TTF-1 | EMA | S100 | GFAP | Synapto-physin | Ki-67 | SSTR2A | pERK | BRAF V600E |
|---|---|---|---|---|---|---|---|---|---|
1 | + | – | + | Focal + | + | 3% | – | + | + |
2 | + | – | + | – | – | < 1% | – | + | – |
3 | + | + | + | – | NP | 4% | Focal + | – | – |
4 | + | – | NP | Focal + | Focal + | NP | – | + | – |
5 | + | NP | NP | + | NP | < 1% | – | + | NP |
6 | + | + | + | + | NP | < 1% | NP | + | NP |
7 | + | Focal + | + | Focal + | NP | 1–3% | – | + | NP |
8 | + | NP | + | NP | NP | NP | – | + | – |
9 | + | – | Focal + | – | NP | < 1% | – | + | NP |
10 (1)a | + | – | – | NP | NP | 5% | NP | NP | NP |
10 (2)a | + | – | – | – | NP | 10% | NP | NP | NP |
10 (3)a | + | NP | NP | – | NP | NP | NP | NP | – |
10 (4)a | + | – | NP | – | NP | 10% | Focal + | + | – |
11a | + | – | + | – | + | 10% | – | + | – |
% Positive | 100.0% | 33.3% | 88.9% | 50.0% | 33.3% | 20.0% | 90.9% | 14.3% |