Case | Age | Sex | Tumor at presentation | Type of surgery | KPS | PIK3CA mutation | MGMT | IDH1 | EGFR | Other alterations | PFS (mo.) | OS (mo.) |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 67 | M | multicentric | PR | 90 | H1047R | u | wt | n.t. | TP53 R248W | 6.3 | 9.7 |
2 | 68 | M | gliomatosis | biopsy | 90 | R88Q | n.t. | wt | N | Â | 3.2 | 5.1 |
3 | 31 | M | leptomeningeal metastasis | biopsy | 90 | H1047R | n.t. | wt | N | Â | 6.6 | 10.9 |
4 | 42 | F | single lesion | PR | 100 | R88Q | m | wt | N | TP53 R273C | 12.4 | 54.9 |
5 | 72 | F | single lesion | GTR | 90 | R88Q | m | wt | N | Â | 5.3 | 10.6 |
6 | 35 | F | multicentric | GTR | 90 | Q546R | u | wt | amp | Â | 26.6 | 32.4 |
7 | 25 | M | multicentric | biopsy | 80 | R88Q | m | wt | N | Â | 6.9 | 19.1 |
8 | 65 | F | single lesion | GTR | 100 | Q546K | m | wt | N | Â | 7.6 | 36.9 |
9 | 43 | M | single lesion | PR | 90 | E545K | u | wt | N | Â | 5.7 | 11 |
10 | 32 | M | single lesion | PR | 100 | H1047R | m | wt | N | Â | 13.8 | 17.7* |
11 | 54 | M | single lesion | GTR | 100 | E542K | m | wt | N | Â | 34.8* | 34.8* |
12 | 57 | M | gliomatosis | biopsy | 80 | H1047Y | m | wt | N | Â | 6.6 | 21.2 |
13 | 51 | M | single lesion | GTR | 100 | H1047R | m | wt | amp | Â | 14.9 | 31.1 |