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Table 3 Patients demographics for Ch2 cholinergic neuronal count and hippocampal CA2 cholinergic varicosity quantification

From: Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson’s disease with cognitive decline

Diagnosis PD PD-MCI PDD
n 8 4 16
M:F (% M) 4:4 (50%) 3:1 (75%) 13:3 (81.3%)
Mean age at onset (SD) 62.13 (8.68) 62.25 (13.72) 65.31 (12.40)
Mean age at death (SD) 73.50 (5.90) 81.00 (8.04) 78.19 (5.97)
Mean duration of disease (SD) 11.38 (5.71) 19.00 (5.72) 12.81 (8.30)
Mean post-mortem interval (hours) 31.00 14.00 27.63
Median Braak αSN stage 6 6 6
Median Braak tau stage 1 2 2