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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Tau and TDP-43 accumulation of the basal nucleus of Meynert in individuals with cerebral lobar infarcts or hemorrhage

Fig. 6

Grading the anti-phosphorylated TDP-43 (pTDP-43) structure in the BNM. pTDP-43 immunoreactive neuronal cytoplasmic inclusions (NCIs), glial cytoplasmic inclusions (GCIs), and neuronal intranuclear inclusions (NIIs) were semi-quantitatively scored as 0–3 depending on their total number: 0 = none; 1 = 1–3; 2 = 4–9; 3 = ≥10. pTDP-43 immunoreactive dystrophic neurites (DNs) were semi-quantitatively scored as 0 to 3: 0, absent; 1, sparse; 2, moderate; 3, severe. The grades of the pTDP immunoreactive NCIs/GCIs/NIIs and DNs were significantly higher on the BNM-affected side than on the BNM-unaffected side (p = 0.01, p < 0.01, respectively)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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