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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: A pathogenic tau fragment compromises microtubules, disrupts insulin signaling and induces the unfolded protein response

Fig. 1

Abnormal phosphorylation of Tau35. a Western blots of CHO-FL and CHO-Tau35 cell lysates probed with antibodies against total and phosphorylated tau (AT8: pSer202/pThr205; AT180: pThr231; and PHF1: pSer396/pSer404). Molecular weight markers (kDa) are shown on the left. b Graphs show the ratio of phosphorylated/total tau in CHO-FL and CHO-Tau35 cells, standardized to CHO-FL cell values (100%). Values represent mean ± S.E.M., n = 3–4. Student’s t-test, **P < 0.01

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