Table 2 Variations of brain amyloid peptide level in APPSWE and WT mice after 5-HIAA or 5-HTP treatment
WT NT | WT 5HIAA | Tg NT | Tg 5HIAA | Tg 5HTP | ||
|---|---|---|---|---|---|---|
Aβ40 | 109.2 | 88.6 | 3285 | 1996 | 1031 | Mean (pg/total proteins) |
100 | 81 | 100 | 61 | 31 | Mean compared with NT (%) | |
0 | −19 | 0 | −39 | −69 | % of variation compared to corresponding NT | |
Aβ42 | 25.2 | 15.3 | 2544 | 2192 | 1408 | Mean (pg/total proteins) |
100 | 61 | 100 | 86 | 55 | Mean compared with NT (%) | |
0 | −39 | 0 | −14 | −45 | % of variation compared to corresponding NT |