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Table 1 Variations of brain amyloid peptide level in phosphoramidon-treated and control mice after 5-HIAA or vehicle treatment

From: 5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer’s disease

 

Vehicle

5-HIAA

Phosphoramidon

5-HIAA + Phosphoramidon

 

Aβ42

1.2

0.8

2.9

2.4

Mean (pg/total proteins)

100

68

244

199

Mean compared with vehicle (%)

0

−32

144

99

% of variation compared to Vehicle

−144

− 176

0

−45

% of variation compared to Phosphoramidon

Aβ40

8.4

7.2

11.7

10.5

Mean (pg/total proteins)

100

86

140

125

Mean compared with vehicle (%)

0

−14

40

25

% of variation compared to Vehicle

−39

−54

0

−15

% of variation compared to phosphoramidon