Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors

Table 1 Patient characteristics

Total number of enrolled patients		107
Male:female ratio		55: 51 (Unknown, 1)
Observation period (median, range)		49 months (0–219)
Age (median, range)	10 years, (0–76 years)
	< 3	22
	3–18	42
	18<	42
	Unknown	1
Extent of resection of the primary tumors	Total resection	51
	Partial resection/biopsy	47
	Unknown	9
Adjuvant therapy for the primary tumors	Radiation therapy (RTx)	32
	Chemotherapy (CTx)	13
	RTx + CTx	22
	No adjuvant therapy	29
	No data	11
Total number of enrolled samples		113
Tumor locations	Supratentorial	38
	Posterior fossa	63
	Spine	12
Time of surgery for the samples	Primary	91
	Recurrent	18
	Unknown	4
Pathological diagnosis (Institutional diagnosis)	Grade 1	2
	Grade 2	46
	Grade 3	60
	No data of grading	5
Pathological diagnosis (Central diagnosis)	Grade 1	1
	Grade 2	33
	Grade 3	67
	Other diagnoses	12
Molecular status	RELA fusion positive	20
	YAP1 fusion positive	1
	PFA	45
	PFB	15

ISSN: 2051-5960