Skip to main content
Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Immunological analysis of phase II glioblastoma dendritic cell vaccine (Audencel) trial: immune system characteristics influence outcome and Audencel up-regulates Th1-related immunovariables

Fig. 4

Audencel’s effect on the immune system. a Significantly positive correlation between vaccines administered and ELISPOT IFNγ (p = 0.038, n = 22), Tbet mRNA (p = 0.006, n = 34), Th1 transcription factors (combined qRT-PCR measurement of Tbet and IFNγ mRNA, p = 0.006, n = 34) and ELISPOT IL-2 (p = 0.001, n = 26). b Significantly negative correlation for blood Treg polarization (p = 0.036, n = 34) and Treg cells (p = 0.034, n = 34). The plots depicted in a and b show all available time points from all available patients (n = patients)

Back to article page