NMDA receptors mediate synaptic depression, but not spine loss in the dentate gyrus of adult amyloid Beta (Aβ) overexpressing mice

Table 3 Morphological analysis of CT100-overexpressing DG granule cells

GluN1^fl/fl 9w pi
Spine numbers	Control (n = 23)	CT100 (n = 6)	GluN1^−/−(n= 23)	GluN1^−/− + CT100 (n = 10)
	1.54 [1.25–1.84]	2.22 [1.95–2.37]	1.73 [1.54–1.9]	1.51 [1.34–1.62]	Kruskal-Wallis: p = 0.0015; Dunn’s posttest: control vs CT100 p = 0.0026; control vs GluN1^−/− p = 0.1332; GluN1^−/− vs GluN1^−/− + CT100 p = 0.1119

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