Nuclear poly(ADP-ribose) activity is a therapeutic target in amyotrophic lateral sclerosis

Table 3 PAR immunoreactivity in patients with no known neurological disease

#	Diagnosis	Region analyzed	PAR in MN nuclei	PAR in MN cytoplasm
1	normal	cervical	0	0
2	normal	cervical	0	++
3	normal	cervical	++	++
4	normal	cervical	0	++
5	normal	cervical	0	0
6	normal	cervical	0	++
7	normal	lumbar	+	+
8	normal	cervical	0	+
9	normal	lumbar	0	++
10	normal	cervical	0	++
11	normal	cervical	0	++
12	normal	cervical	0	++
13	normal	cervical	++	++
14	normal	thoracic	0	++
15	normal	cervical	0	++
16	normal	cervical	0	++

Abbreviations: #: case number. Normal diagnosed neurologically normal. F female, M, male. PAR poly(ADP-ribose). MN motor neuron

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