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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms

Fig. 5

ME turquoise consists of two sub-modules correlated to injury status. a Scatter plot for ME turquoise module showing the correlation between module membership and gene significance. The degree of association between MM and GS was evaluated by Pearson correlation. Correlation value and p value are indicated in the plot. b The pheatmap shows normalized gene expression values beside module eigengene expression values for each sample for ME turquoise. The pheatmap function aggregated the module into 2 sub-modules (Cluster 1 and Cluster 2) by hierarchical clustering. c-d Tables of top assigned GO terms are shown above representative networks for (c) cluster 1 and (d) cluster 2. Hub genes are identified in red font. Size of the nodes represents the module membership value and width of the edge represents the weight of the connection

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