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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: The presubiculum is preserved from neurodegenerative changes in Alzheimer’s disease

Fig. 7

Immunohistochemical analysis of annexins in the presubiculum and entorhinal cortex. Immunohistochemical analysis of Annexin A1 (d-f) and Annnexin A2 (g-i) compared with Aβ deposition (a-c). Serial sections were immunostained for Aβ to identify the ‘lake-like’ Aβ deposit found in the presubiculum (arrows), with image of higher magnification showing the different Aβ morphologies in the presubiculum (b) and entorhinal cortex (c). Positive Annexin A1 and Annexin A2 staining was observed in the entorhinal cortex (f and i) compared to a lack of positive staining in the presubiculum (e and h). Bar in A represents 250 μm in a, d and g and 50 μm in rest of panels

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