Tumor ID | Age/sex | Tumor location | Presenting symptoms | Radiographic pattern | Glial component | Pathogenic genetic alterations identified | Chromosomal gains/losses | Extent of resection | Recurrence or progression | Time to recurrence or progression (years) | Length of follow-up (years) |
---|---|---|---|---|---|---|---|---|---|---|---|
SF-GG-01 | 5Â M | Temporal lobe | seizures | cystic and solid | astrocytic | BRAF p.V600E | none | gross total | no | 0.1 | 0.1 |
SF-GG-02 | 8Â M | Occipital lobe | seizures | multicystic | astrocytic | BRAF p.V600E | none | gross total | no | 0.4 | 0.4 |
SF-GG-03 | 14 M | Occipital lobe | seizures | N/A | astrocytic | BRAF p.V600E, CDKN2A/B HD, PTEN p.R173C (s) | +distal 3q, − 9 | gross total | yes (P) | 1.8 | 1.8 |
SF-GG-04 | 11Â M | Temporal lobe | seizures | N/A | astrocytic | BRAF p.V600E | none | subtotal | yes (R) | 4.4 | 4.4 |
SF-GG-05 | 12 F | Temporal lobe | seizures | N/A | astrocytic | BRAF p.V600E | + 7, + 9, + 12 | unknown | yes (P) | 1.8 | 1.8 |
SF-GG-06 | 12Â F | Temporal lobe | seizures | cystic and solid | astrocytic | BRAF p.V600E | none | gross total | no | 0.5 | 0.5 |
SF-GG-07 | 30 M | Temporal lobe | seizures | N/A | astrocytic | BRAF p.V600E | -1p, −16q | gross total | no | 0.0 | 0.0 |
SF-GG-08 | 27 M | Temporal lobe | seizures | N/A | astrocytic | BRAF p.V600E | + 5, + 7, + 8, + 11, + 12, + 15, + 16, + 19, + 20, + 21 | gross total | no | 0.1 | 0.1 |
SF-GG-09 | 34Â M | Temporal lobe | seizures | solid | astrocytic | BRAF p.V600E, CDKN2A/B HD | -9 | gross total | no | 0.4 | 0.4 |
SF-GG-10 | 37 M | Temporal lobe | seizures | N/A | astrocytic | BRAF p.V600E | + 5 | gross total | no | 9.4 | 9.4 |
SF-GG-11 | 25 F | Temporal lobe | seizures | cyst with mural nodule | astrocytic | BRAF p.V600E, CDKN2A/B HD | -1p, −9 | gross total | no | 6.7 | 6.7 |
SF-GG-12 | 41Â F | Temporal lobe | seizures | cystic and solid | astrocytic | BRAF p.V600E | none | gross total | no | 9.2 | 9.2 |
SF-GG-13 | 63Â M | Parietal lobe | seizures | cyst with mural nodule | astrocytic | BRAF p.V600E | -1p, +19p | gross total | no | 0.0 | 0.0 |
SF-GG-14 | 15Â F | Cerebellum | headaches | cystic and solid | astrocytic | BRAF p.V600E | none | gross total | no | 14.8 | 14.8 |
SF-GG-15 | 13Â M | Cerebellum | asymptomatic | complex heterogeneous | astrocytic | BRAF p.V600E | none | subtotal | yes (P) | 10.4 | 10.4 |
SF-GG-16 | 30Â F | Cerebellum | nystagmus | complex heterogeneous | astrocytic | BRAF p.V600E | none | subtotal | no | 13.8 | 13.8 |
SF-GG-17 | 8Â M | Thalamus | headache | complex heterogeneous | astrocytic | BRAF p.V600E | none | biopsy | no | 0.0 | 0.0 |
SF-GG-18 | 12Â M | Thalamus | dystonia | N/A | astrocytic | BRAF p.V600E | none | biopsy | yes (P) | 29.3 | 29.3 |
SF-GG-19 | 7Â M | Occipital lobe | seizures | cyst with mural nodule | astrocytic | BRAF p.T599_W604delinsTDG | none | gross total | no | 14.1 | 14.1 |
SF-GG-20 | 19Â F | Temporal lobe | seizures | solid | astrocytic | BRAF p.R506delinsRVLR | none | gross total | no | 0.2 | 0.2 |
SF-GG-21 | 29 M | Temporal lobe | seizures | cystic and solid | astrocytic | BRAF p.R506delinsRSTQ | + 5, + 6, + 7, + 11, + 18 | subtotal | no | 1.8 | 1.8 |
SF-GG-22 | 23Â F | Temporal lobe | seizures | cyst with mural nodule | astrocytic | BRAF p.L505delinsLEYLS | none | unknown | no | 0.0 | 0.0 |
SF-GG-23 | 41Â F | Parietal lobe | visual distortion | solid multinodular | astrocytic | BRAF p.R506delinsRVLR | none | gross total | yes (P) | 8.1 | 8.1 |
SF-GG-24 | 5Â F | Spinal cord | asymptomatic | cystic and solid | astrocytic | KIAA1549-BRAF fusion | none | subtotal | no | 0.2 | 0.2 |
SF-GG-25 | 17Â F | Spinal cord | leg weakness | complex heterogeneous | astrocytic | KIAA1549-BRAF fusion | none | gross total | no | 4.5 | 4.5 |
SF-GG-26 | 9Â F | Temporal lobe | seizures | complex heterogeneous | astrocytic | CDC42BPB-BRAF fusion | -interstitial 17p | subtotal | yes (R) | 2.2 | 2.2 |
SF-GG-27 | 8 F | Occipital lobe | seizures | solid | astrocytic | KLHL7-BRAF fusion | + 7 | gross total | no | 1.4 | 1.4 |
SF-GG-28 | 48 M | Frontal lobe | seizures | cyst with mural nodule | astrocytic | ERC2-RAF1 fusion | + 3, −interstitial 3p, + 5, + 7 | gross total | no | 0.5 | 0.5 |
SF-GG-29 | 32Â F | Insula | seizures | cyst with mural nodule | astrocytic | KRAS p.Q61K | none | gross total | no | 0.0 | 0.0 |
SF-GG-30 | 24Â M | Temporal lobe | seizures | cyst with mural nodule | astrocytic | KRAS p.Q61K | none | gross total | no | 1.0 | 1.0 |
SF-GG-31 | 28 M | Temporal lobe | headaches | cystic and solid | astrocytic | germline NF1 p.Q514frameshift w/ somatic LOH | + 4, + 5, + 7, + 8, + 9, + 12, + 15, −17p, −18p, + 22 | gross total | no | 5.9 | 5.9 |
SF-GG-32 | 35Â M | Frontal lobe | paresthesias | solid | oligodendroglial | FGFR1-TACC1 fusion | none | subtotal | no | 1.4 | 1.4 |
SF-GG-33 | 59Â F | Temporal lobe | seizures | multicystic | astrocytic | FGFR1 p.N546Â K | none | gross total | no | 5.9 | 5.9 |
SF-GG-34 | 7Â M | Temporal lobe | seizures | N/A | oligodendroglial | FGFR2-KIAA1598 fusion | none | gross total | no | 5.3 | 5.3 |
SF-GG-35 | 35Â M | Parietal lobe | unknown | complex heterogeneous | oligodendroglial | FGFR2-INA fusion | -portions of 10 | unknown | yes (P) | 9.1 | 9.1 |
SF-GG-36 | 37Â F | Parietal lobe | leg weakness | N/A | astrocytic | FGFR2 exon 17 splice site mutation | none | subtotal | no | 7.5 | 7.5 |
SF-GG-37 | 2Â M | Frontal lobe | seizures | microcystic | astrocytic | ABL2-GAB2 fusion | none | subtotal | no | 0.3 | 0.3 |
SF-GG-38 | 53Â F | Occipital lobe | asymptomatic | N/A | astrocytic | none identified | none | gross total | no | 0.0 | 0.0 |
SF-GG-39 | 0Â F | Cerebellum | nystagmus | cystic and solid | astrocytic | none identified | none | gross total | no | 14.9 | 14.9 |
SF-GG-40 | 10Â M | Spinal cord | arm weakness | N/A | astrocytic | none identified | none | gross total | no | 14.3 | 14.3 |