Fig. 2

Histologic features of gangliogliomas with different genetic alterations in the MAP kinase signaling pathway. a Ganglioglioma in the temporal lobe of a 27 year old man with BRAF p.V600E mutation (SF-GG-08). b Ganglioglioma in the occipital lobe of a 14 year old boy with BRAF p.V600E mutation and CDKN2A homozygous deletion (SF-GG-03). c Ganglioglioma in the temporal lobe of a 23 year old woman with BRAF p.L505delinsLEYLS mutation (SF-GG-22). d Ganglioglioma in the spinal cord of a 5 year old girl with KIAA1549-BRAF gene fusion (SF-GG-24). e Ganglioglioma in the frontal lobe of a 48 year old man with ERC2-RAF1 gene fusion (SF-GG-28). f Ganglioglioma in the temporal lobe of a 7 year old boy with FGFR2-KIAA1598 gene fusion (SF-GG-34)