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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Testing of therapies in a novel nebulin nemaline myopathy model demonstrate a lack of efficacy

Fig. 4

Quantification of muscle function in neb−/− mutants at 6 dpf. Quantification of the a) normalized distance and b) speed travelled by neb−/− mutants at 6 dpf supplemented with either L-tyrosine, taurine, L-carnitine, creatine, or water (H2O). Error bars represent median±interquartile range for three independent experiments (for a; n = 81,79,51 neb−/− for L-tyrosine; n = 82,89,59 neb−/− for taurine; n = 82,82,42 neb−/− for L-carnitine; n = 87,79,46 neb−/− for creatine, and n = 87,96,42 neb−/− for water and for b; n = 81,79,51 neb−/− for L-tyrosine; n = 82,89,59 neb−/− for taurine; n = 82,82,42 neb−/− for L-carnitine; n = 92,79,46 neb−/− for creatine, and n = 87,96,42 neb−/− for water per experiment). ns = not significant

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