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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: D409H GBA1 mutation accelerates the progression of pathology in A53T α-synuclein transgenic mouse model

Fig. 6

D409H GBA1 expression shows the activation of pathology-associated microglia and astrocyte activation in the SNpc of A53T α-synuclein transgenic mice. a, Iba-1 immunoreactive microglia were observed in the SNpc region of the indicated genotypes at 6 months of age. The scale bar is 50 μm. b, The number of microglia was counted. c, GFAP immunoreactive astrocytes were observed in the SNpc region of the indicated genotypes at 6 months of age. The scale bar is 50 μm. d, The signals were measured using ImageJ

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Acta Neuropathologica Communications

ISSN: 2051-5960

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