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Table 1 Demographic Data of Cases Included in the Study

From: Large inter- and intra-case variability of first generation tau PET ligand binding in neurodegenerative dementias

Case Sex AAO AAD Brain Weight (g) Braak Stage Thal Phase ABC Score
CTRL1 F 68 1330 0 0 A0B0C0
CTRL2 M 71 1480 I 0 A0B1C0
CTRL3 F 80 1242 II 0 A0B1C0
CTRL4 M 89 1448 III 3 A2B2C1
AD1 F 50 66 906 VI 5 A3B3C3
AD2 M 63 73 1269 VI 5 A3B3C3
AD3 M 52 68 1234 VI 5 A3B3C3
AD4 M 63 74 1022 VI 5 A3B3C3
FTDP1a) M 55 66 1208 0 0 A0B0C0
FTDP2b) M 68 74 1048 II 2 A1B1C1
FTDP3c) M 59 66 1399 0 0 A0B0C0
PICK1 M 57 62 1166 III 1 A1B2C1
PICK2 M 54 64 1040 0 3 A2B0C1
PSP1 M 62 74 1580 0 2 A1B0C1
PSP2 F 60 68 1177 0 1 A1B0C1
CBD F 62 69 1100 0 0 A0B0C0
  1. Abbreviations: CTRL, control; AD, Alzheimer’s disease; FTDP, frontotemporal dementia with parkinsonism linked to chromosome 17; PICK, Pick’s disease; PSP, progressive supranuclear palsy; CBD, corticobasal degeneration; MAPT, microtubule associated protein tau gene locus; M/F, male/female; AAO, age at onset; AAD, age at death
  2. Genetic variants: a) MAPT R406W; b) MAPT Δ280K; c) MAPT 10 + 16
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