TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease

Table 1 Frequency of TDP-43 pathology in brain regions by stage in 547 participants

Regions	TDP-43 stages					Total TDP-43 positive cases by brain regions n, %
	1	2	3	4	5
	n = 206	n = 112	n = 85	n = 83	n = 61
	37.7%	20.5%	15.5%	15.2%	11.1%
Amygdala	206	112	85	83	61	547, 100
Entorhinal Cortex	0	92	83	82	60	317, 58.0
Hippocampus, CA1	0	84	74	82	59	299, 54.7
Hippocampus, dentate gyrus	0	60	59	76	59	244, 44.6
Anterior temporal pole cortex	0	0	85	83	61	229, 41.9
Midtemporal cortex	0	0	0	70	57	127, 23.2
Orbital frontal cortex	0	0	0	32	57	89, 16.3
Midfrontal cortex	0	0	0	0	61	61, 11.1

ISSN: 2051-5960