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Table 1 Frequency of TDP-43 pathology in brain regions by stage in 547 participants

From: TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease

Regions TDP-43 stages Total TDP-43 positive cases by brain regions n, %
1 2 3 4 5
n = 206 n = 112 n = 85 n = 83 n = 61
37.7% 20.5% 15.5% 15.2% 11.1%
Amygdala 206 112 85 83 61 547, 100
Entorhinal Cortex 0 92 83 82 60 317, 58.0
Hippocampus, CA1 0 84 74 82 59 299, 54.7
Hippocampus, dentate gyrus 0 60 59 76 59 244, 44.6
Anterior temporal pole cortex 0 0 85 83 61 229, 41.9
Midtemporal cortex 0 0 0 70 57 127, 23.2
Orbital frontal cortex 0 0 0 32 57 89, 16.3
Midfrontal cortex 0 0 0 0 61 61, 11.1
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