Fig. 2
From: Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression
Time-course of induced Aβ deposition in the brains of Aβ-inoculated AppNL-F mice. Female mice were inoculated with partially purified Aβ aggregates from a TgCRND8 mouse (TgCRND8–1 sample) and brains were analyzed by Aβ immunohistochemistry (4G8 antibody) at the indicated dpi. Representative sections from the corpus callosum of inoculated mice are shown. Induced Aβ deposition was first apparent at 60 dpi (red arrow). Scale bar: 20 μm