Table 3 Characteristics of patients included in the immunofluorescence study
From: Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer’s disease brain
Variables | Controls (n = 6) | AD (n = 9) | P-value |
|---|---|---|---|
Age at death (years) | |||
Median [IQR] | 70.0 [68.0–73.0] | 81.0 [72.0–85.0] | NS |
Range | 58.0–82.0 | 69.0–88.0 | |
Female gender, n (%) | 2 (33.3) | 5 (50.0) | NS |
Post mosterm interval | |||
Median [IQR] | 10.0 [5.5–23.0] | 24.5 [16.0–29.0] | NS |
Range | 5.0–24.0 | 8.0–44.0 | |
“A” Thal - n of patients (%) | < 0.001 | ||
3 (4 and 5) | 0 (0) | 8 (88.9) | |
2 (3) | 0 (0) | 1 (11.1) | |
1 (1 and 2) | 4 (66.7) | 0 (0) | |
0 (None) | 2 (33.3) | 0 (0) | |
“B” Braak Stage - n of patients (%) | < 0.001 | ||
3 (V and VI) | 0 (0) | 9 (100) | |
2 (III and IV) | 1 (16.7) | 0 (0) | |
1 (I and II) | 3 (50) | 0 (0) | |
0 (None) | 2 (33.3) | 0 (0) | |