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Table 2 Characteristics of patients included in the western blot study

From: Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer’s disease brain

Variables

Controls (n = 6)

AD (n = 10)

P-value

Age at death (years)

 Median [IQR]

74.0 [70.5–80.0]

81.0 [78.0–85.0]

0.032

 Range

67.0–86.0

62.0–89.0

 

 Female gender, n (%)

2 (33.3)

5 (55.5)

NS

Post mosterm interval

 Median [IQR]

17.5 [12.0–22.0]

8 [7.5–23.0]

NS

 Range

4.0–36.0

6.0–50.0

 

 Missing (n)

1

0

 

“A” Thal - n of patients (%)

  

< 0.001

 3 (4 and 5)

0 (0)

8 (80)

 

 2 (3)

0 (0)

1 (10)

 

 1 (1 and 2)

1 (16.7)

1 (10)

 

 0 (None)

5 (83.3)

0 (0)

 

“B” Braak Stage - n of patients (%)

  

< 0.001

 3 (V and VI)

0 (0)

10 (100)

 

 2 (III and IV)

0 (0)

0 (0)

 

 1 (I and II)

5 (83.3)

0 (0)

 

 0 (None)

1 (16.7)

0 (0)