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Table 3 Accumulated data obtained from the ultrastructural analysis of neuropil from layer II of the TEC. All volume data are corrected for shrinkage factor

From: Three-dimensional analysis of synapses in the transentorhinal cortex of Alzheimer’s disease patients

Group No. AS synapses No. SS synapses No. all synapses % AS Synapses (mean ± SD) % SS Synapses (mean ± SD) CF volume (μm3) No. AS synapses/μm3 (mean ± SD) No. SS synapses/μm3 (mean ± SD) No. synapses/μm3 (mean ± SD) Distance to nearest neighbor (nm; mean ± SD)
Control 2545 111 2656 95.64 ± 1.24 4.36 ± 1.24 5295 0.49 ± 0.14 0.02 ± 0.01 0.51 ± 0.14 791.54 ± 74.47
Alzheimer 1887 103 1990 94.47 ± 0.72 5.53 ± 0.72 5266 0.35 ± 0.14 0.02 ± 0.01 0.37 ± 0.15 881.50 ± 129.37
  1. All includes AS+SS synapses, AS asymmetric synapses, No. number, SD standard deviation, SS symmetric synapses
  2. The data for individual cases are shown in Additional file 1: Table S2