Table 3 Accumulated data obtained from the ultrastructural analysis of neuropil from layer II of the TEC. All volume data are corrected for shrinkage factor
From: Three-dimensional analysis of synapses in the transentorhinal cortex of Alzheimer’s disease patients
Group | No. AS synapses | No. SS synapses | No. all synapses | % AS Synapses (mean ± SD) | % SS Synapses (mean ± SD) | CF volume (μm3) | No. AS synapses/μm3 (mean ± SD) | No. SS synapses/μm3 (mean ± SD) | No. synapses/μm3 (mean ± SD) | Distance to nearest neighbor (nm; mean ± SD) |
|---|---|---|---|---|---|---|---|---|---|---|
Control | 2545 | 111 | 2656 | 95.64 ± 1.24 | 4.36 ± 1.24 | 5295 | 0.49 ± 0.14 | 0.02 ± 0.01 | 0.51 ± 0.14 | 791.54 ± 74.47 |
Alzheimer | 1887 | 103 | 1990 | 94.47 ± 0.72 | 5.53 ± 0.72 | 5266 | 0.35 ± 0.14 | 0.02 ± 0.01 | 0.37 ± 0.15 | 881.50 ± 129.37 |