Skip to main content
Fig. 8 | Acta Neuropathologica Communications

Fig. 8

From: Surfen, a proteoglycan binding agent, reduces inflammation but inhibits remyelination in murine models of Multiple Sclerosis

Fig. 8

Surfen injected 2 days after lysolecithin (lysophosphatidylcholine, LPC) delays remyelination of lesions in the corpus callosum. Surfen is administered 2 days after LPC injection. a Left sided linear graphic shows treatment schedule, while right sided panels show data for each time point, as well as representative images of lesions in the corpus callosum. b The area of the lesions is plotted against time from LPC injection for groups indicated. Data is shown as mean ± SEM; significant differences between matched surfen and vehicle injected groups are indicated (* = P < 0.05); Scale bars: LPC, LPC + Sham = 300 μm; LPC border = 100 μm, Vehicle/Surfen = 500 μm

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us