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Table 2 Significant differences in the plasma metabolites of AQP4-Ab NMOSD, RRMS, and MOG-Ab disease

From: Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease

  AQP4-Ab NMOSD RRMS MOG-Ab
Concentration of large LDL particles   
Size of HDL particles   
Glucose   
Cholesterol concentration in large HDL (subclass A)   
Large LDL particles   
Small HDL particles   
Phosphocholine/lipoprotein   
Scyllo-inositol   
Lysine/creatinine/creatine    
Histidine    
Large HDL particles    
Lactate    
Unsaturated lipid    
Alanine    
Formate   
Leucine   
Myo-inositol   
  1. Increases and decreases relative to the other two disease classifications are indicated with ↑ and ↓ respectively
  2. Metabolites listed were identified as discriminatory by OPLS-DA