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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Distinct functional consequences of ECEL1/DINE missense mutations in the pathogenesis of congenital contracture disorders

Fig. 3

Axonal arborization defects in G607S hindlimb and foot muscles. Motor nerves were visualized by GFP immunoreactivity to compare the innervation pattern between E17.5 wild-type (a) and homozygous knock-in mutant (b, c) foot muscles. The terminal number of motor nerves is individually plotted. Black bars represent the median. The number of motor nerve terminals was significantly reduced in both G607S and C760R mutant muscles (d). Kruskal-Wallis test followed by the Steel-Dwass test, *p < 0.05. n = 5. Scale bar: 100 μm (a–c)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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