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Table 2 Changes in cytokine/chemokine levels in plasma and in different brain regions as a consequence of blast exposure, measured at 40 weeks post-blast exposure

From: Lack of chronic neuroinflammation in the absence of focal hemorrhage in a rat model of low-energy blast-induced TBI

  L-Hipp R-Hipp L-Amy R-Amy L-AC R-AC L-PC R-PC Plasma
EGF NC NC NC NC NC NC NC NC NC
Eotaxin NC NC NC NC NC NC NC NC NC
Fractalkine NC NC NC NC NC NC NC NC NC
G-CSF NC NC NC NC NC NC NC NC NC
GM-CSF NC NC NC NC NC NC NC NC NC
GRO/KC NC NC NC NC NC NC NC NC NC
IFNγ NC NC NC NC NC NC NC NC NC
IL-10 NC NC NC NC NC NC NC NC NC
IL-12p70 NC NC NC NC NC NC NC NC NC
IL-13 NC NC NC NC NC NC NC NC NC
IL-18 NC NC NC NC NC NC NC NC NC
IL-1α NC NC NC NC 1.3↓p = 0.03 NC NC NC NC
IL-1β NC NC NC NC NC NC NC NC NC
IL-2 NC NC NC 1.3↑p = 0.06 NC NC NC NC NC
IL-4 NC 1.3↑p = 0.06 NC NC NC NC NC NC NC
IL-5 NC NC NC NC 1.3↓p = 0.04 NC NC NC NC
IL-6 NC NC NC 1.3↑p = 0.06 NC NC NC NC NC
IL-17A NC NC NC NC NC NC NC NC ND
IP-10 NC NC NC NC NC NC NC NC NC
Leptin NC NC NC NC 1.2↓p = 0.04 NC 1.2↓p = 0.04 NC NC
LIX NC NC NC NC NC NC NC NC NC
MCP-1 NC NC NC NC NC NC NC NC NC
MIP-1α NC NC NC NC NC NC NC NC NC
MIP-2 NC NC NC NC NC NC NC NC NC
RANTES NC NC NC NC NC NC NC NC NC
TNFα NC NC NC NC NC NC NC NC NC
VEGF NC NC NC 1.3↑p = 0.03 NC NC NC NC NC
  1. Up or down arrows indicate increased or decreased levels in blast-exposed versus control animals.The respective p value is indicated. NC, no change; L or R indicate left or right subregion, respectively. Hipp, Hippocampus; Amy, Amygdala; AC, Anterior cortex; PC, Posterior cortex