Lack of chronic neuroinflammation in the absence of focal hemorrhage in a rat model of low-energy blast-induced TBI

Table 2 Changes in cytokine/chemokine levels in plasma and in different brain regions as a consequence of blast exposure, measured at 40 weeks post-blast exposure

	L-Hipp	R-Hipp	L-Amy	R-Amy	L-AC	R-AC	L-PC	R-PC	Plasma
EGF	NC	NC	NC	NC	NC	NC	NC	NC	NC
Eotaxin	NC	NC	NC	NC	NC	NC	NC	NC	NC
Fractalkine	NC	NC	NC	NC	NC	NC	NC	NC	NC
G-CSF	NC	NC	NC	NC	NC	NC	NC	NC	NC
GM-CSF	NC	NC	NC	NC	NC	NC	NC	NC	NC
GRO/KC	NC	NC	NC	NC	NC	NC	NC	NC	NC
IFNγ	NC	NC	NC	NC	NC	NC	NC	NC	NC
IL-10	NC	NC	NC	NC	NC	NC	NC	NC	NC
IL-12p70	NC	NC	NC	NC	NC	NC	NC	NC	NC
IL-13	NC	NC	NC	NC	NC	NC	NC	NC	NC
IL-18	NC	NC	NC	NC	NC	NC	NC	NC	NC
IL-1α	NC	NC	NC	NC	1.3↓p = 0.03	NC	NC	NC	NC
IL-1β	NC	NC	NC	NC	NC	NC	NC	NC	NC
IL-2	NC	NC	NC	1.3↑p = 0.06	NC	NC	NC	NC	NC
IL-4	NC	1.3↑p = 0.06	NC	NC	NC	NC	NC	NC	NC
IL-5	NC	NC	NC	NC	1.3↓p = 0.04	NC	NC	NC	NC
IL-6	NC	NC	NC	1.3↑p = 0.06	NC	NC	NC	NC	NC
IL-17A	NC	NC	NC	NC	NC	NC	NC	NC	ND
IP-10	NC	NC	NC	NC	NC	NC	NC	NC	NC
Leptin	NC	NC	NC	NC	1.2↓p = 0.04	NC	1.2↓p = 0.04	NC	NC
LIX	NC	NC	NC	NC	NC	NC	NC	NC	NC
MCP-1	NC	NC	NC	NC	NC	NC	NC	NC	NC
MIP-1α	NC	NC	NC	NC	NC	NC	NC	NC	NC
MIP-2	NC	NC	NC	NC	NC	NC	NC	NC	NC
RANTES	NC	NC	NC	NC	NC	NC	NC	NC	NC
TNFα	NC	NC	NC	NC	NC	NC	NC	NC	NC
VEGF	NC	NC	NC	1.3↑p = 0.03	NC	NC	NC	NC	NC

Up or down arrows indicate increased or decreased levels in blast-exposed versus control animals.The respective p value is indicated. NC, no change; L or R indicate left or right subregion, respectively. Hipp, Hippocampus; Amy, Amygdala; AC, Anterior cortex; PC, Posterior cortex

ISSN: 2051-5960