Fig. 2
From: Alzheimer’s disease pathological lesions activate the spleen tyrosine kinase
pSyk is increased in dystrophic neurites of Aβ-overexpressing mice. Representative confocal image of depicting the cortex of 116.5 ± 13.5-week-old Tg PS1/APPsw mice stained for sAPPβ (purple), pSyk (green, a), BACE1 (green, b), Iba-1 (red). Nuclei were stained with DAPI (blue). a pSyk was accumulated in dystrophic neurites positive for sAPPβ (a) and BACE1 (b). The scale bars represent 10 μm