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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Are exosomes the vehicle for protein aggregate propagation in neurodegenerative diseases?

Fig. 1

Kinetic principle of protein aggregation underlies the intercellular aggregate transmission. a Simplified scheme illustrating the kinetics of protein fibrillation and seeded polymerization. Addition of pre-formed fibrils drastically reduced the lag phase. b Illustration of seeded polymerization principle in cell-to-cell aggregate transmission. When protein aggregates are transferred from one cell to another, the transferred aggregates could act as ‘seeds’ in the recipient cells

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