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Table 1 Summary of new tau monoclonal antibodies

From: Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau

Antibody Antigen Specificity Isotype
PHF2 391EIVYKpSPVVSGDTpSPRHLS409 phosphorylated pS396/S404 IgG1
PHF15 391EIVYKpSPVVSGDTpSPRHLS409 phosphorylated pS396/S404 IgG1
PFH17 391EIVYKpSPVVSGDTpSPRHLS409 phosphorylated pS396/S404 nd
PHF20 391EIVYKpSPVVSGDTpSPRHLS409 phosphorylated S404 IgG2B
PHF22 391EIVYKpSPVVSGDTpSPRHLS409 phosphorylated S396/S404 IgG1
1H5 193DRSGYSpSPGpSPGpTPGSRSR211 prefers phosphorylated tau IgM
2D1 193DRSGYSpSPGpSPGpTPGSRSR211 phosphorylation independent IgG1
3C9 193DRSGYSpSPGpSPGpTPGSRSR211 prefers phosphorylated T205 IgG1
4A10 193DRSGYSpSPGpSPGpTPGSRSR211 phosphorylation-independent IgG1
5F2 193DRSGYSpSPGpSPGpTPGSRSR211 phosphorylation-independent IgG1
6G12 193DRSGYSpSPGpSPGpTPGSRSR211 phosphorylated T205 IgG1
7F2 193DRSGYSpSPGpSPGpTPGSRSR211 phosphorylated T205 IgG1
8G5 193DRSGYSpSPGpSPGpTPGSRSR211 phosphorylated T205 IgG1
10G12 193DRSGYSpSPGpSPGpTPGSRSR211 phosphorylated T205 IgG1
  1. Listed are the antigens used to generate each antibody, the specificity for each antibody, and their isotypes