Fig. 4From: Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal deathNEFH mutation destabilised NEFL filamentous network in vitro. a Confocal images of transfected SH-EP with eGFP-NEFL or untagged NEFH WT or untagged NEFH-CAE (c3008_3010delGA mutation). Untagged NEFH proteins were stained using anti-NEFH antibody Smi32. Scale bar: 10 μm. b Confocal images of co-transfected SH-EP with eGFP-NEFL and untagged NEFH WT or CAE. The mutant untagged NEFH-CAE proteins form aggresome containing NEFL, p62/SQSTM1 and LC3b. Scale bar: 10 μmBack to article page