Fig. 4
From: Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours
H3-G34R antibody immunostaining correlates with histone H3.3 genotyping. Representative IHC using H3-G34R antibody on a H3 G34R mutated tumor section shows a strong nuclear positivity in nearly all tumor cells but no staining in the nuclei of endothelial cells (top). WT H3 tumor is negative with H3-G34R antibody by IHC (middle). H3 K27M thalamic tumor stained negative for H3-G34R antibody by IHC (bottom). (scale bar 100Â ÎĽm)