Fig. 4
From: Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice
Neuronal density is unchanged in murine APP-deficient mice. Representative brain sections immunostained for NeuN (neuronal nuclei) and contrasted using haematoxylin revealed no significant differences in neuronal density between mAPP0/0 a and mAPP+/+ mice b at 150 d. Semi-automatic evaluation of digitised slides confirmed similar density of neurons in both groups c. (Scale bar: 250 μm; unpaired t-test with Welch’s correction displayed no significant differences; n ≥ 10)