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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice

Fig. 4

Neuronal density is unchanged in murine APP-deficient mice. Representative brain sections immunostained for NeuN (neuronal nuclei) and contrasted using haematoxylin revealed no significant differences in neuronal density between mAPP0/0 a and mAPP+/+ mice b at 150 d. Semi-automatic evaluation of digitised slides confirmed similar density of neurons in both groups c. (Scale bar: 250 μm; unpaired t-test with Welch’s correction displayed no significant differences; n ≥ 10)

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