Fig. 1
From: Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis
Clinical course, EEG and MRI of the index patient. Time axis of disease development with main symptoms, treatments and findings. a EEG excerpt in average potential reference montage shows right-sided periodic lateralized epileptiform discharges (PLED); bar: 1 s. b Coronal T2-FLAIR MRI on admission shows hyperintensity in the right superior temporal gyrus, compatible with inflammation. c Coronally reconstructed 3D-FLAIR MRI shows progression after 30 days. Abbreviations: MPT, methylprednisolone pulse therapy; T2-FLAIR, T2-weighted fluid attenuation inversion recovery; 3D-FLAIR, three dimensionally acquired fluid attenuation inversion recovery. Red square indicates site of brain biopsy