Table 1 Summary of clinical and pathological characteristics of all donors
From: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology
Diagnosis | Age (years) | Brain weight (g) | Education (years) | DRS | Braak stage | Plaques (counts/0.1 mm2) | Tangles (counts/0.01 mm2) | Amyloid angiopathy (score) | Lewy bodies (score) |
|---|---|---|---|---|---|---|---|---|---|
Ctl (N = 3) | 82.33 ± 5 | 1142 ± 111 | 14 ± 3.4 | 140 ± 1 | 0 | 4.67 ± 0.67 | 0 | 0 | 0 |
AD (N = 3) | 81.3 ± 4.7 | 1100 ± 156 | 12 ± 0 | 72.7 ± 8.3 | 6.2 ± 0 | 47.3 ± 4.6 | 6.7 ± 4.2 | 3 | 0 |
DLB (N = 3) | 77 ± 13.9 | 1237 ± 9.7 | 14.7 ± 3.1 | 104 ± 11 | 4.2 ± 2.8 | 33 ± 1 | 2 ± 1 | 0.7 ± 0.2 | 3 |