Skip to main content
Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Identification and description of three families with familial Alzheimer disease that segregate variants in the SORL1 gene

Fig. 2

Pedigree of family PED.27. The family segregates the SORL1 variant c.3050-2A > G (p.Gly1017-Glu1074) in two generations. Index patient (III:1) included in the targeted gene sequencing is marked with an *. The numbers inside the symbol for I:4–7 (4) and in II:4–6 (3) indicates multiple individuals. The genetic status for variant c.3050-2A > G is indicated “carrier” for heterozygotes, “wildtype” when absent, and “unknown” if DNA was unavailable. Diagnosis refers to the clinical diagnosis. Onset refers to first observation of dementia symptoms, and APOE indicates the ε-alleles. Diagnosis refers to the clinical diagnosis

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us