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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene

Fig. 1

Immunostaining for hnRNPs in dentate gyrus of the hippocampus in normal human brain. hnRNP A1 is localised mostly in cell cytoplasm (a), whereas hnRNP A2 (b,c) and hnRNP A3 (d) are mostly nuclear. In cases of FTLD-TDP type C there is some ‘nuclear clearing’ of hnRNP A2 (arrowed in c). Immunoperoxidase, microscope magnification, ×400

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