Fig. 4

Effects of taxifolin treatment on CBF and CVR in WT mice. CBF and CVR was not changed between vehicle and taxifolin treated WT mice. a Representative images showing resting CBF measured by laser speckle flowmetry. In vehicle-treated (left), and taxifolin-treated (right), WT mice at 8 months of age receiving vehicle or taxifolin for 7 months. b A histogram showing CBF (n = 5–8 for each). c Temporal profiles of %increase in CBF in WT mice aged 8 months with vehicle (open circle) or taxifolin (filled circle) for 7 months (n = 3 each). Error bars indicate ± SD (b) and ± SE (c)